Michel Weber, Éduquer (à) l’anarchie. Essai sur les conséquences de la praxis philosophique, Louvain-la-Neuve, Les Éditions Chromatika, 2008. (978-2-930517-03-2 ; 239 p. ; 20 € ; -/- L'idéal philosophique incarné par la vie et l'œuvre d’Alfred North Whitehead (1861–1947) est, plus que jamais, d'une actualité brûlante. Il requiert que la philosophie soit une discipline vécue afin qu'elle puisse demeurer une discipline vivante. Quel posture socio-politique suggère-t-il ? Le concept d’anarchie permet de nommer à la fois l’état présent du monde (...) globalisé (le « chaos constructif » voulu par le néolibéralisme) et la réponse qui s’impose : le communautarisme libertaire, c’est-à-dire la redynamisation de la démocratie participative. Or, le monde de l’éducation se situe précisément en ce point de bifurcation : ou bien il succombe aux assauts du marché et nous nous dirigeons vers la barbarie ; ou bien il résiste et la Vie reprend ses droits. The philosophical ideal embodied by the life and works of Alfred North Whitehead (1861–1947) is, more than ever, a burning question. It requires that philosophy be a lived discipline so that it can remain a living discipline. What does this ideal entail in the socio-political sphere? The concept of anarchy allows a straightforward discussion of both the current state of affairs in a globalized world (the “constructive chaos” fostered by neoliberalism) and the necessary reaction : libertarian communautarism, which constitutes a re-energization of participative democracy. Now, the world of education lies precisely at that bifurcation point. Either it gives way beneath the attacks of the “market” and we are heading towards barbary; or it resists and Life regains its rights. (shrink)

Michel Weber, L’Épreuve de la philosophie. Essai sur les fondements de la praxis philosophique, Louvain-la-Neuve, Les Éditions Chromatika, 2008. (978-2-930517-02-5 ; 141 p. ; 15 € ; ) Peu connu en francophonie, l’entretien — ou la « pratique » — philosophique est une activité qui plonge ses racines dans l’héritage socratique. Faire l’épreuve de la philosophie, c’est se soumettre à l’exigence de la vie authentique, telle qu’elle pilote un type particulier de dialogue : le dialogue maïeutique, celui qui accouche (...) les âmes. Il s’agit ici de situer les enjeux de la pratique philosophique et d’en établir les fondements, c’est-à-dire de montrer ce qui fait sa spécificité indépendamment des disciplines existant déjà dans le domaine de la santé mentale. Little known in the French-speaking world, philosophical counselling is a practice that is rooted in Socrates' and Epicurus legacies. The philosophical ordeal, i.e., to put philosophy to the test requires a double event taking place during the dialogue between the philosophical practitioner and the visitor (to use Achenbach's term). On the one hand, the practitioner accepts to have her philosophical standpoint assessed by its maieutic capacity to relieve human suffering. On the other, the visitor endorses in his own way the commitment to authenticity that is specific to philosophical life. This book provides the foundations for a practice primarily inspired by A. N. Whitehead’s organic and processual philosophy as it enforces a radical creativity. Its visionary stance is furthermore confronted with Pierre Hadot’s “spiritual exercises” and its efficacy supported by James’ pragmatism. (shrink)

L’article exploite l’occasion rare d’étudier ensemble une statue et la construction où elle était présentée et mise en valeur. Les fragments de la statue comme de son baldaquin ont été trouvés ensemble lors de la fouille de 1931. Le baldaquin consiste en un petit édicule corinthien à deux colonnes, ouvert en façade et sur les côtés, accolé au mur Sud de la curie. La légèreté de sa construction comparée à la massivité de la statue exécutée d’un seul bloc, implique qu’il (...) a été construit autour de la statue, après sa mise en place et son achèvement. La statue assise de Fortuna se présentait de face, tournée vers l’espace qui tenait lieu de basilique civile au forum. L’emplacement où elle se trouve lui donne ainsi tout son sens. L’ensemble a été mis en place au moment des grands travaux de la deuxième phase architecturale du forum, dans le troisième quart du iie s. p.C., et détruit par le séisme qui a gravement affecté les bâtiments du forum vers le début du vie s. (shrink)

Michel Weber, Essai sur la gnose de Harvard. Whitehead apocryphe, Louvain-la-Neuve, Les Éditions Chromatika, 2011. (978-2-930517-26-1, 292 p., 20 €) L’objet de ce livre consiste en une éludication croisée de la philosophie organique whiteheadienne et de la gnose thomasienne. Il cherche à répondre à deux questions. La philosophie de l’événement, du processus ou du procès, d’Alfred North Whitehead (1861–1947) possède-t-elle, volens nolens, un fond gnostique syrien ? L’évangile apocryphe de Thomas, le gnostique juif qui a couché par écrit l’enseignement (...) de Jésus probablement trente ans après son décès, offrant ainsi une source qui pourrait être plus ancienne que les évangiles canoniques et leur hypothétique texte-racine Q, gagne-t-il a être lu à partir de prémisses whiteheadiennes ? Michel Weber dirige le Centre de philosophie pratique « Chromatiques whiteheadiennes » à Bruxelles. Il a publié plus de cinquante ouvrages scientifiques, dont La Dialectique de l’intuition chez A. N. Whitehead (2005), Whitehead’s Pancreativism (2006 & 2011) et L’Épreuve de la philosophie (2008). (shrink)

L’article présente diverses observations faites au forum de Philippes au fil des ans, difficiles à intégrer dans une publication définitive. I. Plusieurs creusements affectent les dalles, surtout dans la partie nord-ouest du dallage : six logements pour rabattre des anneaux ayant peut-être servi aux officiels de la colonie pour attacher leur monture, et cinq trous carrés (deux sont traversants) qui pourraient avoir servi à fixer des mâts. II. Publication de 12 jeux de marelle (un seul avait déjà été illustré) dont (...) la répartition peut donner des indications sur la fréquentation réelle de la place ; en appendice, présentation succincte de 5 autres marelles (4 au marché, 1 dans la rue du Commerce). III. Fragment de cadran solaire en marbre dont le lieu d’exposition pourrait avoir été la rue du Commerce à proximité du forum. IV. Fragment d’une plaque de latrine trouvée dans un remblai, probablement antérieure au milieu du IIe s. p. C., mais dont l’emplacement d’origine ne peut être déterminé. (shrink)

L’article présente deux résultats qui trouveraient mal leur place dans la publication définitive en cours d’élaboration. I. Compléments d’ordre archéologique à la publication de la dédicace du dallage CIPh II 1, 66, et proposition pour la remettre à sa place initiale. Elle était située longitudinalement au milieu de la place de façon à pouvoir être lue depuis la terrasse haute. Comme la suivante, la première phase monumentale a été aménagée aux frais des notables de la colonie. II. Publication d’une table (...) à mesure connue par une allusion et une photographie, et d’un autre fragment très mutilé. La table à mesure située face au tabularium, impossible à dater, est taillée en sous‑face pour emboîter les degrés du monument, au moins à partir du milieu du iie s. p. C. Examen des difficultés que soulève sa présence dans un espace qui n'avait plus de rôle commercial à cette époque. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Comparative Philosophy and Method: Contemporary Practices and Future Possibilities ed. by Steven Burik, Robert Smid and Ralph WeberDouglas L. Berger (bio)Comparative Philosophy and Method: Contemporary Practices and Future Possibilities. Edited by Steven Burik, Robert Smid and Ralph Weber. London and New York: Bloomsbury Academic, 2023. Pp. vi + 272. Paperback $40.28, isbn 978-1-350-29704-3.The editors Steven Burik, Robert Smid and Ralph Weber, who have all made important (...) revisions to the theory of comparative philosophical method, have pulled together the contributions of ten other influential scholars in the field and their own work into this much-needed collection of essays. There has been much written about the methodology of comparative philosophy in the last hundred years. More recent reflections in this field have been strongly fueled by post-colonial evaluations as well as a proliferation of methodological approaches. Nonetheless, some consensus on what methods the field should adopt and to what ends still needs overt discussion. The editors argue in an Introduction and Epilogue to the volume that, now faced with the "obstacles" of often conflicting principles and aims of different methodological approaches which leads to their frequent mutual rejection, there is need for a wide acceptance of pluralism in the methodology of comparative philosophy (pp. 4–5). This methodological pluralism, for the editors, should be understood in two senses. Firstly, there should be a broad-based "methodological commitment to pluralism," which amounts to an acceptance that there is an existing plurality of philosophical traditions in the world which have very different foundational insights and worldviews (p. 254). Secondly, the fact that the plurality of philosophical traditions actually exhibits quite different approaches ought, despite any individual comparativist's preferred method, compel us to accept that this diversity is best dealt with by a plurality of research approaches (pp. 254–55). That is to say that, while the editors both acknowledge and endorse the particular specializations of any and all scholars engaged in intercultural philosophy, they urge each scholar to accept that both a descriptive and prescriptive pluralism of philosophical methodologies are necessary for the continued flourishing of the field. In order to demonstrate this descriptive and prescriptive pluralism, the editors organize the volume into what they call five "constellations" of discussion (p. 8).In the first "constellation" labeled "Necessary Conditions," Robert Neville, Jaap [End Page 1] van Brakel and Lin Ma offer general and detailed frameworks for what sorts of assumptions are needed for any comparative philosophical research to proceed fruitfully. Neville, while happily admitting that we need to be vigilant about biases and other limitations when crossing into other traditions, insists that philosophers need to at once be searching for the truth in any given comparison of ideas, while simultaneously always reflectively constructing the right categories on the basis of which the comparison may be justified and sound (pp. 22–27). Van Brakel and Ma present in their co-authored essay an elaborate blueprint for comparative research. This blueprint, while also conceding that there can never be "any one right interpretation" of any individual text, much less whole traditions, posit a basic "family resemblance principle" which highlights "mutually recognizable human practices" as the basic condition enabling comparative reflection in the first place (pp. 34–39).In the second "constellation," entitled "Generalization and Essentialization," Roger Ames and François Jullien insist in various ways that, while the essentialism that bedeviled previous eras of philosophy in general and comparative philosophy in particular should be rejected, generalizations are still fundamentally necessary to crystalize the most important ways in which traditions are distinct from one another. Ames, defending himself against recent allegations of essentialism in his approach, insists that the field needs to be supported by both a "self-reflective hermeneutical sensitivity" which acknowledges the positionality of the inquirer as well as a commitment to "search within the soil" of, in his case, the Chinese philosophical tradition for its own models of meaning (p. 58). To the latter end, Ames defends accurate generalizations which can help us understand "the language, the customs and the life-forms of a living tradition" since these, contrary to suspicions, aid us in preventing essentialization in comparative work (p. 63). Jullien... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Imagining Karma, Ethical Transformation in Amerindian, Buddhist, and Greek RebirthA. L. HermanImagining Karma, Ethical Transformation in Amerindian, Buddhist, and Greek Rebirth. By Gananath Obeyesekere. Berkeley: University of California Press, 2002. 448 pp.Gananath Obeyesekere, professor emeritus of anthropology at Princeton University, is probably one of the world's greatest living anthropologists. The proof of that assertion lies in this his latest work on comparative anthropology, a study of the concept (...) and practice of rebirth—"reincarnation" as he calls it—from ancient Greece and India to modern West Africa, Melanesia, and North America. In what follows let me briefly set forth what I understand his central thesis to be, the evidence for it, and the conclusions to be drawn from it. I will end with two very modest problems connected with this altogether intriguing and brilliant investigation into the doctrine of rebirth.As a modified structural anthropologist, Gananath Obeyesekere rejects the rationalist model structuralism of Claude Levi-Strauss. He follows instead the lead of two of his empiricist predecessors, Max Weber and Fernand Braudel, pointing out that structures, types, or models "are constructions of scholars, not universals waiting to be discovered" (p. 351). Consequently, as this book aptly proves, Obeyesekere's own "imagined" models are based on parole data following the actual language of the cultures being studied.Obeyesekere thus begins his book with an elementary rebirth structure based on such parole. He refers to this primitive, first structure as "rebirth eschatology," which entails the rebirth of a deceased's soul into the body of a newborn relative of the deceased but without any determining ethical component as found in the more sophisticated and complex "karmic eschatologies." Such ethically neutral kin group rebirths are found among certain small-scale societies in West Africa, the Trobriand Islands, the Northwest American coast tribes, and the Inuits (Eskimos). Obeyesekere [End Page 303] draws extensively on field studies of these groups to bolster his conclusions about them. This simple rebirth eschatology is non-Indic in origin, Obeyesekere claims, since no evidence of influences have been found between these practitioners of rebirth eschatology and work relating to the Indic religions (Hinduism and Buddhism). The entry of the soul into postdeath life, either in this world or the world of the ancestors, depends not at all, consequently, on one's this-worldly behavior such that "morality does not affect the fate of the soul after death" (p. 74).Obeyesekere turns next to the "transformation" of this rebirth eschatology. It occurs with the introduction of the concept of ethicization, "the processes whereby morally right or wrong action becomes a religiously right or wrong action that in turn affects a person's destiny after death" (p. 75). It is Obeyesekere's contention that when ethicization is systematically introduced into any rebirth eschatology the latter must logically transform itself into a so-called "karmic eschatology." In other words, this second topological model or conceptual structure, karmic eschatology, the new ethicized rebirth eschatology, says that the otherworld for the dead is not simply a way station for departed souls waiting to be reborn, but rather that otherworld is now a place of retribution and punishment. Kinship affiliation alone no longer determines who goes where after death but moral action does. My own guess is that rebirth eschatology was introduced to answer the question of why the grandchild resembles the deceased grandparent. Karmic eschatology, on the other hand, was probably introduced to solve a more complex and sophisticated puzzle: Why is it, if there really is justice in the universe, that the wicked never get appropriately punished and the good never get sufficiently rewarded? At this stage of transformation, the law of karma, or some other principle of universal justice, now says that everyone gets what's coming to them, either in this life or the next, and that rebirth is necessary to make that principle of justice workable.1 In arguing that "rebirth cannot be divorced from ethics; it looks as if it is generated from ethics" (p. 82), Obeyesekere would seem to concur that karmic eschatology was introduced to answer the question: Why do the wicked seem to prosper and the good appear to suffer?Following... (shrink)

Turkey has passed the import substitution economic model to a new model of the economy called open out since 1980. Along with the neoliberal policies implemented, the process of integration with the global economy has begun. The incomes of the religious people who cannot be excluded from the effects of this articulation also increased and their consumption behaviors has changed. On the other hand, some transport elements, especially the media, have enabled consumption codes to reach different segments. The new values (...) emerged in this process also caused transformations in individual consumption trends. In this study, the "Scale of Consumption Dynamics" (SCD) was developed in order to identify the trends of consumption of devotees and to find out how they changed. Quantitative research approach was adopted in the study and the datas were collected by face-to-face survey technique. The individuals included in our sample were selected by quota sampling. In this study, an expression pool was created as a result of literature review, expert opinion consultation, brainstorming with academicians and observations. The validity and reliability analysis of the scale was made using different statistics through the SPSS program. As a result of these steps, the dimensions of the scale consisting of 16 items and 3 dimensions are called "showy consumption", "wasteful consumption" and "religious priority consumption". Summary: The first studies on consumption history and sociology belong to Marx, Weber, Veblen and Simmel. In these studies consumption is examined as a part of production process and consumption forms were investigated as a social class aspect. Consumption phenomenon was later studied under critical approach (Frankfurt School) with Adorno, Max Horkheimer, Herbert Marcuse and Erich Fromm’s theories. Theorists at Frankfurt School study how social structure steers individuals to consumption. After the 1970’s, the meaning of consumption phenomenon has changed. There are studies by Jean Baudrillard, Mike Featherstone, George Ritzer, and Zygmunt Bauman on changing phenomenon of consumption. It is widely believed that modern consumption phenomenon was originated in the USA after the World War II. After the war Keynesian economic policies and Fordist consumption forms later influenced other Western nations. After 1950’s and 1960’s mass consumption was initiated in the USA and except very poor sections of the nations, other social classes, it started to spread out in Europe, the USA, and other countries. In 1970’s and 1980’s, it has merged with individuals’ identity definitions. After 1980’s in Turkey a new economic policy instead of import substitution was adopted. In application along with neo liberal policies, Turkey started to integrate to the rest of the World. Religious people as well influenced these changes and their incomes have increased along with their consumption habits. In addition to media, some other forms of communication channels have carried new consumption habits to other sections of the society. With the increased effects of mass communication media, new social sections have emerged and their cultural characteristics have become the norms of the whole society. A new values created in this process also transformed the consumption habits. In this article, in order to assess consumption habits of religious people as it is now and to understand which direction these habits evolve, Consumption Dynamics Scale (CDS) has been developed. Scales are widely used when a researcher tries to identify and measure respondents’ feelings and ideas on a subject matter. There are different scales used in social sciences such as Thurstone, Likert, Guttman, and Bogardus that are among the most widely used ones. A Likert Type scale has been used in this study. In the first phase of the study and pilot study 5 point Likert scale and in the second phase of the study 10 point Likert scales was used to collect the data. We could not come across with any study in the literature on investigating consumption characteristics Dynamics of individuals with a formal religious education. In the study, quantitative research method has been adopted and the research data has been collected with face to face administration of the survey instrument. The scale development phase lasted about 6 months from August, 2016. Based on 3% error rate, we determined to sufficient sample size as 516, yet we reached 600 individuals and end up with 563 usable responses. Sample has been determined with quota sampling methodology. We formed a pool of statements based on literature review, expert opinion, brain storming with academicians. 49 questions have been selected from the question pool where 93 questions were found, then they are merged, some questions are changed or totally eliminated and final 30 questioned questionnaires made ready for pilot study. Two pilot studies have been carried out. In the first pilot study, 47 people are reached and 30 questions with Likert scales have been administered. In the second phase of the study, 10 point Likert scales with 57 questions has been given to 54 individuals. After pilot studies, data was analyzed with SPSS 20 version and 32 questioned final survey instrument has been formed. In order to check sufficiency of data set for Factor Analysis Kaisser-Meyer-Olkin (KMO) test and the relationships among variables Bartlett test were used. Sample composed of 563 responses revealed significant results (3358,808, p=0,000) and KMO test revealed (KMO=0,812) value. After expletory factor analysis, factor loading less than 0,40 were deleted from the scale. Hence the final structure is composed of 29 questions with 8 different factors. The reliability of scales were calculated with Cronbach Alfa analysis separately for each dimension. After reliability analysis, items with 0,60 and less reliability score were taken out from the scales. Finally 16 items were made up 3 dimensions namely “ostentatious consumption”, “wasteful consumption”, and “religious priority consumption”. The items in Factor 1 are related with luxury, fashion and statue, in Factor 2 desire to make more shopping, purchase without need, advertisement and showcase, and factor 3 religious sensitive reference focus and religion first purchasing are decided as appropriate names. Based on the analysis, measurement was decided valid and sound. Therefore, this study is believed to contribute significantly to the existing literature. (shrink)

The last thirty years has witnessed an explosion of scholarly books and articles on Locke which, claims Harpham, has "recast our most basic understanding of Locke as a historical actor and political theorist, the Two Treatises as a document, and liberalism as a coherent tradition of political discourse". The seven articles in this volume attempt to assess this "new scholarship," which is described as revisionist and historicist. This volume is now probably the best introduction to the "new scholarship." The introduction (...) by Edward Harpham, "Locke's Two Treatises in Perspective," and the bibliography provide a nice summary of key ideas, books, and articles. The essence of the new perspective is best stated by Richard Ascraft [[sic]] in "The Politics of Locke's Two Treatises of Government": "Locke's thought is thus both philosophically more conservative and politically more radical than we have hitherto supposed. In short, Locke is at once closer to Aristotle and Hooker and to the levelers and Sidney than the prevailing interpretations of his political thought maintain". Ashcraft attempts to separate Locke from the philosophy of Hobbes on such issues as resistance, toleration, justice and natural law, obligation; he directs his argument against Macpherson and Strauss, whose presences haunt the borders of the new scholarship. Eldon Eisenach, in his "Religion and Locke's Two Treatises of Government," interprets Locke's philosophy as marked by a deep skepticism regarding the reach of natural reason and informed by a "deep faith in the efficacy of biblical revelation" as the source of our moral and political duties. Eisenach comes close to dissenting from the new scholarship by wondering whether "Dunn and Ashcraft" are whistling in the dark concerning the coherence of Locke's "worldview"; but he closes ranks with the assertion that the Essay lays out a path to salvation. Eisenach concludes that Locke is not antireligious and secular, but a defender of biblical Christianity. The new scholarship must emphasize all the more a "spiritualist and assertively evangelical Locke". David Resnick, in "Rationality and the Two Treatises," attempts to recover the portrait of Locke as an antitraditionalist, committed to a critical rationalism. Resnick uses Weber's theory of rationality to render a consistent account of Locke's social analysis. Yet Resnick also insists that Locke's political philosophy is not self-interested and atomistic but is rooted in a fully Christian worldview: "Locke's deeply held theological convictions about the existence, benevolence and rationality of God ground his reasoning in a metaphysically stable framework". This religious assumption provides a basis for Locke's "rationality." But a new inconsistency is opened up by this resolution--a rationalism rooted in religious faith, by a philosopher who continually urged their distinction. Karen Iversen Vaughn, in "The Economic Background to Locke's Two Treatises of Government," attempts to correct the new scholarship's neglect of the economic premises of Locke's political philosophy; this neglect is part of an overreaction to Macpherson, but Vaughn offers a moderate economic interpretation of Locke. Vaughn shows the importance of rational self-interest in economic behavior, the necessity of political society to set conditions for economic pursuit: limit on sovereign power is an example of self-interest and evidence that "economic aspects of man's behavior permeated all aspects of life". Further, "civil society requires enforceable rules to contain the self-seeking actions of all men, so that life, liberty and property can be protected". Vaughn's essay opens the back door to the "self-interested" Locke of the "old scholarship." Ronald Hamowy, in "Cato's Letters, John Locke, and the Republican Paradigm," also seeks to redress the imbalance of the new scholarship, arguing that Locke's philosophy was not displaced by the civic humanist tradition and republican virtue. He offers a detailed analysis of Cato's Letters by John Tenchard and Thomas Gordon. Like Locke, "Cato" defines political authority in terms of inalienable rights. His analysis of liberty is strikingly Lockean, and not republican. Pocock's assessment of Locke's irrelevance to Whiggism and the American founding must be rejected. In the final essay, "Locke's Two Treatises and Contemporary Thought: Freedom, Community and the Liberal Tradition," Stephen L. Newman compares contemporary American libertarian and communitarian alternatives to the liberal welfare state. Newman offers a very trenchant criticism of libertarianism as decidedly non-Lockean by dint of its utter depoliticization of all behavior and its tendency to restore the execution of natural law to the private citizen and private groups. On the other hand, communitarianism fails to provide a sufficiently specific and robust notion of the common good, and more consistent writers like Walzer and Barber fall back not upon a teleological community, but autonomy mixed with participation. Locke's distinction of politics from economics, family, and social groups still provides the most workable and realistic account of politics available in the modern world; hence Newman concludes that libertarianism and communitarianism offer "impoverished" political theories. (shrink)

In Britain doctors and others concerned with the treatment of offenders in prison may consult the Butler Report (see Focus, pp 157) and specialist journals, but these sources are concerned with the system in Britain only. In America the situation is different, both in organization and in certain attitudes. Dr Peter L Sissons has therefore provided a companion article to that of Dr Paul Bowden (page 163) describing the various medical issues in prisons. The main difference between the treatment of (...) offenders in prisons in America and in Britain lies in the nature of the federal system which means that each state may operate a different system in a variety of prisons and prison medical services are as various. Nationally, the prison systems are 'structured to treat and cure the offender'. Therefore it follows that the prison medical officer is only one of the professionals concerned with this 'cure' of the offender. This principle also applies to any form of research: medical research in prisons is part of a programme which covers a wide field of social and judicial research. The prison medical officer (where there is one) has of course to look after sick prisoners, and the American idea of 'cure' is also expressed in the need for more corrective surgery where, for example, it is necessary to remove physical impediments to social rehabilitation. But a doctor is only found on the staff of those institutions which are large: in the smaller prisons there may be only first-aid facilities, and no specially appointed doctor in the community. Moreover medicines are often dispensed by medical auxiliaries who are sometimes prisoners themselves. Finally, in America prisoners are regularly invited to volunteer as subjects for medical and social research for which they are paid. In short, although it is hoped to 'cure' a prisoner he is a criminal first and a patient second. (shrink)

The heme‐containing cytochromes P‐450 are a ubiquitous family of monooxygenase isozymes responsible for the oxidative metabolism of a wide variety of endogenous as well as exogenous compounds. Many of the compounds metabolized by this enzyme system are effectively detoxified and converted to derivatives more easily eliminated from the organism. However, some compounds can be activated to reactive species capable of eliciting a cascade of toxic lesions, including cancer. Since its discovery nearly 30 years ago, the cytochrome P‐450 enzyme system has (...) received a great deal of attention, particularly in the areas of their mechanisms of metabolism, range of substrate specificity, the purification and characterization of the multiple isozymes and, more recently, the regulation of expression of specific forms. This review will discuss current notions concerning the expression of at least one cytochrome P‐450 isozyme and future directions that should lead to a more complete understanding of cytochrome P‐450 gene expression in general, particularly as it impacts upon biochemical pharmacology. (shrink)

The article is a critique of malcolm and the wittgensteinians and their criticisms of russell which the author finds to be "prosecuting russell on false charges." (staff).

Note by the Editor of Voprosy filosofii: The presidium of the USSR Academy of Sciences has decided to hold, in Moscow in December 1980, the Third USSR Conference on Philosophical Problems of Contemporary Natural Science, dedicated to the one hundred and tenth anniversary of the birth of V. I. Lenin, and has established an organizing committee headed by P. N. Fedoseev, vice-president of the Academy, to prepare and conduct the conference.

I should like to begin by removing a misconception to which the title of this lecture may possibly give rise. My concern is not with general propositions regarding certain fairly well-attested human characteristics of the kind to which historians may, from time to time, advert in the course of their work or to which they may appeal in support of the account provided of some particular event or occurrence. I am not myself an historian, and for me to make ex (...) cathedra pronouncements on such topics as these might well seem to constitute an unjustifiable intrusion upon a field about which I am not qualified professionally to speak. My subject lies within the sphere of philosophy of history rather than of history proper; it belongs, in other words, to a branch of philosophical inquiry, and as such relates, not to empirical facts and events of the sort to which the practising historian addresses himself, but to those assumptions, categories and modes of procedure that are, or are believed to be, intrinsic to historical thought and discourse. In this general context I wish to discuss two approaches to the problem of elucidating the character of historical knowledge and explanation. Both of the approaches I have in mind have achieved a considerable measure of support at the present time; they have also been widely understood as offering profoundly divergent — indeed, diametrically opposed — views of what is central to the structure of historical thinking and to the type of activity upon which the historian is essentially engaged. It has on occasions been suggested that what — amongst other things — divides adherents to the views in question is the fact that they are committed to radically different conceptions of the subject-matter of the historical studies; that is to say, of human beings and their activities. In the light of this fundamental disagreement, it is argued, many of the more intractable controversies that have arisen concerning the concepts and interpretative schemes in terms of which it is possible or legitimate to treat the human past become readily intelligible. In what follows I want to examine this claim. First, however, let me give a brief, and necessarily somewhat crude, outline of the two positions I have referred to, starting with one that is often described as ‘positivist’. (shrink)